Colorado Animal Specialty & Emergency (CASE)
Biobanking Osteosarcoma as a Nexus for Evaluation and Staging (BONES)
CURRENTLY ENROLLING
SUMMARY OF STUDY:
Osteosarcoma is the most prevalent form of bone cancer in dogs, sharing many biological similarities with the disease in humans. Unfortunately, even when a tumor is completely removed through surgery, over 90% of dogs eventually die because the cancer spreads to their lungs.
The BONES study seeks to create a “biobank” by collecting tissue and blood samples from dogs with osteosarcoma over time. These valuable samples will be shared with leading bone cancer researchers to help them better understand why this cancer spreads and becomes resistant to treatment. By following enrolled dogs with regular check-ups and lung x-rays, the study also helps monitor for cancer progression. This research aims to significantly advance knowledge of bone cancer in both dogs and humans, and may provide dogs who show cancer progression with an opportunity to enroll in a separate, innovative surgical trial.
INCLUSION CRITERIA:
Suspected to have osteosarcoma based on clinical and/or x-ray findings
Dogs weighing more than 5 kg
Dogs must undergo a local control procedure (surgery, cryoablation, or radiation therapy)
FINANCIAL INCENTIVES:
Participating pet owners will receive:
Screening testing including blood work and chest x-rays$500 credit towards the cost of surgery and histopathology processing. Recheck chest x-rays every 3 months
Costs you are responsible for:
Any surgical costs that exceed the $500 credit provided by the study.
Costs for any additional treatments you choose to pursue, such as chemotherapy or other diagnostic tests outside of the study requirements.
All other costs related to disease monitoring and treatment are not covered.
WHAT TO EXPECT:
Screening (Day -14 to -1): Before treatment, your dog will be screened for eligibility with a physical exam, blood work, and 3-view thoracic (chest) x-rays. A stool sample will also be collected and you will need to sign an informed consent form.
Surgery (Day 1): Your dog will undergo local therapy to treat the bone tumor.
Follow-up Schedule:
2 Weeks Post-Op (Day 14): A follow-up visit is required for blood and stool sample collection.
Every 3 Months (Days 90, 180, 270, 360): Your dog will have restaging visits that include thoracic x-rays to check for cancer spread to the lungs, as well as blood and stool sample collection.
Disease Progression: If cancer is found to have spread to the lungs, your dog will be evaluated for potential enrollment in the Minimally Invasive Metastasectomy in Canines (MIMIC) clinical trial.
INTERESTED?
Email [email protected]
